
TY  - JOUR
A1  - Brown, DJ 
A1  - Grigg, GW 
A1  - Iwai, Y 
A1  - McAndrew, KN 
A1  - Nagamatsu, T 
A1  - Heeswyck, Rv 
T1  - Purine Analogues as Amplifiers of Phleomycin. V. Thioethers of Several Heterocyclic Systems with One or Two Rings
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1979
VL  - 32
IS  - 12
SP  - 2713
EP  - 2726
KW  - 
UR  - https://doi.org/10.1071/CH9792713 
N2  - Thioethers, appropriate for testing as amplifiers of phleomycin against in vitro cultures of Escherichia coli, are prepared via corresponding thiones in the purine, imidazo[4,5-b(and 4,5-c)]pyridine, pyrazolo[3,4-d]pyrimidine, quinazoline, benzothiazole, benzoxazole, pyrimidine, imidazole, thiazoline, 1,2,4-triazole, s-triazolo[4,3-c(and 1,5-c)]pyrimidine, oxazolo[4,5-b]pyridine, quinoline and 1,3,5-triazine series. Structures are confirmed by N.M.R. spectra. Biological activities are tabulated and discussed in terms of structure. 
ER  -

