
%0 Journal Article
%A Teitei, T 
%T The synthesis of 2-(5-Phenylthiazol-4-y1)benzoic acids
%J Australian Journal of Chemistry
%D 1980/03/01
%V 33
%N 3
%P 605-611
%K 
%R https://doi.org/10.1071/CH9800605
%U https://www.publish.csiro.au/paper/CH9800605 
%X The four-step synthesis of 2-(5-phenylthiazol-4-yl)benzoic acid (2a), and its 2-amino derivatives (2b), required for testing as potential plant growth regulators, is described. The &#945;-bromo ketone (9b) was conveniently prepared from commercially available 3- benzylidenephthalide (8) in two steps, and in turn formed the thiazole esters (12) on treatment with either a mixture of formamide and phosphorus pentasulfide or thiourea. Hydrolysis of the esters (12) furnished the above benzoic acids. 
