
%0 Journal Article
%A Stunzi, H 
%A Harris, LN 
%A Perrin, DD 
%A Teitei, T 
%T Stability constants for metal complexation by isomers of mimosine and related compounds
%J Australian Journal of Chemistry
%D 1980/10/01
%V 33
%N 10
%P 2207-2220
%K 
%R https://doi.org/10.1071/CH9802207
%U https://www.publish.csiro.au/paper/CH9802207 
%X Stability constants for the Mg2+, Ca2+, Cu2+ and Zn2+ complexes of two isomers (2) and (3) of the defleecing agent mimosine (1) have been sought from potentiometric titrations in aqueous solution, 0.15 M KNO3, at 37&#176;. For the interpretation of the results, complex formation of the simpler ligands 3-hydroxypyridin-4(1H)-one (4), its 2-oxo isomer (5) and DL-&#945;-amino-&#946;-(6-oxo-1,6-dihydropyridin-2-yl)propanoic acid (6) was studied. The results with ligand (2) are very similar to those with mimosine, for which a computer blood-plasma model indicates metal chelation under physiological conditions. Ligand (3) is a much weaker complexing agent. 
