
TY  - JOUR
A1  - Hutchison, GI 
A1  - Prager, RH 
A1  - Ward, AD 
T1  - Central nervous system active compounds. III. The synthesis of 4- and 6-substituted caprolactam derivatives by the Schmidt and Beckmann rearrangements
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1980
VL  - 33
IS  - 11
SP  - 2477
EP  - 2486
KW  - 
UR  - https://doi.org/10.1071/CH9802477 
N2  - The synthesis is described of hexahydroazepin-2-ones (caprolactams) bearing 1-4 alkyl or aryl groups at C4 and C6 by the Beckmann or Schmidt reactions on the corresponding cyclohex-2-enone. Further evidence for the mechanism of the Beckmann rearrangement of these unsaturated oximes is advanced. The central nervous system activity of the alkylated caprolactams is reported. 
ER  -

