
TY  - JOUR
A1  - Hutchison, GI 
A1  - Marshall, PA 
A1  - Prager, RH 
A1  - Tippett, JM 
A1  - Ward, AD 
T1  - Central nervous system active compounds. IV. Synthesis of 3-aminobenzylphthalides
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1980
VL  - 33
IS  - 12
SP  - 2699
EP  - 2715
KW  - 
UR  - https://doi.org/10.1071/CH9802699 
N2  - Several 3-aminobenzylphthalides have been prepared by reactions of 3- (2-oxo-1-phenylpropyl)-phthalides with hydrazoic acid or by the Beckmann rearrangement. The corresponding reactions with 3-(2- oxoindanyl)phthalides showed limited success but led to a new synthesis of phthalide-isoquinoline alkaloids. Preliminary biological testing of some of these derivatives indicates that they only have weak central nervous system activity. 
ER  -

