
TY  - JOUR
A1  - Hung, TV 
A1  - Mooney, BA 
A1  - Prager, RH 
A1  - Tippett, JM 
T1  - Central nervous system active compounds. VII. Phthalide synthesis by lithiation of alkoxyaromatics
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1981
VL  - 34
IS  - 2
SP  - 383
EP  - 395
KW  - 
UR  - https://doi.org/10.1071/CH9810383 
N2  - The lithiation of methoxy- and methylenedioxy-bemyl alcohols is described; subsequent reactions with ethyl chloroformate and carbon dioxide to form phthalides have been investigated, and are compared with metallation-carboxylation of alternative substrates. The preparation of phthalideisoquinoline analogues by this method proceeds only in low yields due to the acidity of the benzylic position in the benzylisoquinoline precursor. 
ER  -

