
TY  - JOUR
A1  - Armarego, WLF 
A1  - Waring, P 
T1  - Pterins. VII. Preparation of 6,6-dimethyl-5,6,7,8-tetrahydropterin hydrochloride
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1981
VL  - 34
IS  - 9
SP  - 1921
EP  - 1933
KW  - 
UR  - https://doi.org/10.1071/CH9811921 
N2  - The preparation of 6,6-dimethyl-5,6,7,8-tetrahydropterin (5) hydrochloride, a possible substrate for the phenylalanine hydroxylating system, has been achieved by trimethylsilylating 6-methyl-7,8- dihydropterin, reacting with methyllithium and removing the trimethylsilyl groups. Attempts to prepare this pterin by intramolecular cyclization of 2,5-diamino-6-(2'-hydroxy-2'-methylpropyl)-aminopyrimidin-4(3H)-one (17) gave the isomeric 5,8-diamino-3,3-dimethyl-2,3-dihydroimidazo- [1,2-clpyrimidin-7(1H)-one (20). 
ER  -

