
TY  - JOUR
A1  - Galbraith, M 
A1  - Horn, DS 
A1  - Kelly, B 
A1  - Kinnear, J 
A1  - Martin, M 
A1  - Middleton, E 
A1  - Virgona, CF 
T1  - Moulting Hormones. LIII. the Synthesis and Biological Activity of Some Ecdysone Analogues
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1981
VL  - 34
IS  - 12
SP  - 2607
EP  - 2618
KW  - 
UR  - https://doi.org/10.1071/CH9812607 
N2  - A number of ecdysone analogues were prepared to study the effect of structural changes on biological activity. It was found that analogues with the 5&#945;-configuration or a 3,5-cyclo structure were inactive, that a 3&#946;-hydroxy group enhances activity but is not essential for activity, and that 3&#946;-substituents decrease activity as follows: OMe (60%), OAc (25%) and OEt (10%). The keto diol (3), keto alcohol (9) and amide (36) were found to be highly toxic to mosquito larvae. 
ER  -

