
TY  - JOUR
A1  - Cullen, LJ 
A1  - Sargent, MV 
T1  - Depsidone synthesis. XXII. An alternative synthesis of gangaleoidin
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1981
VL  - 34
IS  - 12
SP  - 2701
EP  - 2703
KW  - 
UR  - https://doi.org/10.1071/CH9812701 
N2  - A new synthesis of the lichen depsidone gangaleoidin (1) (methyl 2,4-dichloro-3-hydroxy-8-methoxy-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][l,4]dioxepin-7-carboxylate) is described. It depends on the oxidation of methyl 4-hydroxy-3-(4',6'-dihydroxy-2'-methylbenzoyl)-6-methoxy-2-methylbenzoate (7)to methyl 6-hydroxy-4,6'-dimethyl-4'-methoxy-2',3-dioxo-2,3-dihydrospiro[benzofuran-2,1'-cyclohexa-3',5'-dienel-5'-carboxylate (8), and the thermolysis of this compound to methyl 3-hydroxy-8-methoxy-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][l,4]dioxepin-7-carboxy1ate (2), which had been previously converted into gangaleoidin (1) by chlorination. 
ER  -

