
%0 Journal Article
%A Wabnitz, Paul A. 
%A Bowie, John H. 
%A Wallace, John C. 
%A Tyler, Michael J. 
%T Peptides from the Skin Glands of the Australian Buzzing Tree Frog <emph type="2">Litoria electrica</emph>. Comparison with the Skin Peptides of the Red Tree Frog <emph type="2">Litoria rubella</emph>
%J Australian Journal of Chemistry
%D 1999/08/19
%V 52
%N 7
%P 639-646
%K 
%R https://doi.org/10.1071/CH98171
%U https://www.publish.csiro.au/paper/CH98171 
%X Eleven peptides have been isolated from the skin glands of the &#8216;buzzing tree frog&#8217; Litoria electrica. The two most abundant peptides are tryptophyllin L 3.1 &#91;Phe Pro Trp Pro (NH2)&#93; and electrin 1 &#91;Phe Val Pro Ile Tyr Met (NH2)&#93;. These peptides show neither significant antimicrobial nor smooth muscle activity. Tryptophyllin L 3.1 is thought to be a neuromodulator or neurotransmitter, and it is similar in structure to the human endomorphins &#91;e.g. Tyr Pro Trp Phe (NH2)&#93; which act on the &#947;-receptor. Both Litoria electrica and the &#8216;red tree frog&#8217; Litoria rubella produce tryptophyllin peptides: it is considered that both species evolved from the same ancestor. 
