
TY  - JOUR
A1  - Gellert, E 
A1  - Kumar, N 
A1  - Tober, D 
T1  - Stereospecific synthesis of tetrahydrobenzisoquinoline derivatives
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1983
VL  - 36
IS  - 1
SP  - 157
EP  - 163
KW  - 
UR  - https://doi.org/10.1071/CH9830157 
N2  - A new synthesis of optically active tetrahydrobenzisoquinolines is described. Cyclization of N-aryl- alkylalanines with retention of configuration was achieved by mild intramolecular Friedel-Crafts acylation. The compounds synthesized this way represent simple analogues of phenanthroindolizidine alkaloids. Some features of the n.m.r. spectra of cyclized and open-chain intermediates are discussed. 
ER  -

