
%0 Journal Article
%A Jackson, MB 
%A Mander, LN 
%A Spotswood, TM 
%T Reduction of N-substituted azetidin-2-ones to azetidines
%J Australian Journal of Chemistry
%D 1983/04/01
%V 36
%N 4
%P 779-788
%K 
%R https://doi.org/10.1071/CH9830779
%U https://www.publish.csiro.au/paper/CH9830779 
%X Reduction of N-substituted azetidin-2-ones to N-substituted azetidines was accomplished rapidlyand in good yield with diborane in tetrahydrofuran and with alane in ether. The stereochemistryof the ring substituents was retained under the reaction conditions. 3-Aminopropanol derivativesformed by reductive ring cleavage were sometimes obtained as by-products in diborane reductionsbut not in alane reductions. The reductions of fourteen azetidin-2-ones to azetidines with diboraneand eighteen with alane are reported. 
