
%0 Journal Article
%A Mcfarlane, EF 
%A Martinic, C 
%T 400-MHz <sup>1</sup>H N.M.R. of adjuvant muramyl dipeptide in dimethyl sulfoxide
%J Australian Journal of Chemistry
%D 1983/06/01
%V 36
%N 6
%P 1087-1096
%K 
%R https://doi.org/10.1071/CH9831087
%U https://www.publish.csiro.au/paper/CH9831087 
%X The minimal active principle, N-acetylmuramyl-L-alanyl-D-isoglutamine* (MDP), of complete Freund's adjuvant was studied in dry dimethyl sulfoxide solutions by 1H n.m.r. at 400 MHz. All resonances except those of the non-anomeric CH protons of the sugar ring were assigned. The &#945;/&#946; anomeric ratio was found to be the same (2 : 1) as reported for the equilibrated aqueous solutions from which the dimethyl sulfoxide solutions were prepared. The present findings indicate that MDP adopts a substantially structured conformation in dimethyl sulfoxide solutions. 
