
%0 Journal Article
%A Brown, DJ 
%A Cowden, WB 
%T Unfused heterobicycles as amplifiers of phleomycin. VII. Some triazolyl-, thiadiazolyl- and oxadiazolyl-pyridines and related pyrimidines
%J Australian Journal of Chemistry
%D 1983/07/01
%V 36
%N 7
%P 1469-1475
%K 
%R https://doi.org/10.1071/CH9831469
%U https://www.publish.csiro.au/paper/CH9831469 
%X Syntheses are described for several 4-(1',2',4'-triazol-3'yl)pyridines, 3-and 4-(1',3',4'-thiadiazol-2'-yl)-pyridines, 3- and 4-(1',3',4'-oxadiazol-2'-yl)pyridines, 5-(1',3',4'-thiadiazol-2'-yl)pyrimidines and 5-(1',3',4'-oxadiazol-2'-yl)pyrimidines, all provided with a &#946;-dimethylaminoethylthio side chain at the 5-position of the five-membered ring. The activities of these compounds as amplifiers of phleomycin-G against an in vitro culture of Escherichia coli B are tabulated and discussed. 
