
%0 Journal Article
%A Grant, HM 
%A Mctigue, P 
%A Ward, DG 
%T The basicities of aliphatic amides
%J Australian Journal of Chemistry
%D 1983/11/01
%V 36
%N 11
%P 2211-2218
%K 
%R https://doi.org/10.1071/CH9832211
%U https://www.publish.csiro.au/paper/CH9832211 
%X We report pKa values in aqueous solution at 298 K of the protonated forms of several aliphatic amides, viz., acetamide (pKa = -0.62 ± 0.07), N-methylacetamide (-0.42 ± 0.03), N,N-dimethyl-acetamide (-0.28 ± 0.03), N,N-dimethylformamide (-1.2 + 0.5), urea (0.053 ± 0.002) and thiourea (-0.9 ± :O.l). pKa values are also reported for protonated acetamide and urea in aqueous solution in the temperature range 5-40ºC and in D2O. A previously described conductimetric method was used for all measurements. 
