
TY  - JOUR
A1  - Grant, HM 
A1  - Mctigue, P 
A1  - Ward, DG 
T1  - The basicities of aliphatic amides
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1983
VL  - 36
IS  - 11
SP  - 2211
EP  - 2218
KW  - 
UR  - https://doi.org/10.1071/CH9832211 
N2  - We report pKa values in aqueous solution at 298 K of the protonated forms of several aliphatic amides, viz., acetamide (pKa = -0.62 ± 0.07), N-methylacetamide (-0.42 ± 0.03), N,N-dimethyl-acetamide (-0.28 ± 0.03), N,N-dimethylformamide (-1.2 + 0.5), urea (0.053 ± 0.002) and thiourea (-0.9 ± :O.l). pKa values are also reported for protonated acetamide and urea in aqueous solution in the temperature range 5-40ºC and in D2O. A previously described conductimetric method was used for all measurements. 
ER  -

