
TY  - JOUR
A1  - Brown, DJ 
A1  - Cowden, WB 
A1  - Lan, S 
A1  - Mori, K 
T1  - Heterocyclic amplifiers of phleomycin. I. Some pyrimidinylpurines, pyrimidinylpteridines and phenylpyrimidines
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1984
VL  - 37
IS  - 1
SP  - 155
EP  - 163
KW  - 
UR  - https://doi.org/10.1071/CH9840155 
N2  - Synthetic routes are described to 5,6-diamino-2,4'-bipyrimidin-4-ones and thence to 2-(pyrimidin-4'-yl)purines and 2-(pyrimidin-4'-yl)pteridines, some of which bear a sulfur- or nitrogen-linked basic side chain; also reported are routes to a series of phenyl- and diphenyl-pyrimidines, to each of which is attached a similar sulfur-, nitrogen-, or oxygen-linked side chain. Members of all the above systems show activity as amplifiers of phleomycin in a bacterial screen but the phenylpyrimidines with a sulfur-linked side chain are especially active. 
ER  -

