
%0 Journal Article
%A Gellert, E 
%A Kumar, N 
%T Stereospecific synthesis of hexahydrobenzopyrroloisoquinoline and tetrahydrobenzisoquinoline derivatives
%J Australian Journal of Chemistry
%D 1984/04/01
%V 37
%N 4
%P 819-829
%K 
%R https://doi.org/10.1071/CH9840819
%U https://www.publish.csiro.au/paper/CH9840819 
%X New optically active hexahydrobenzopyrroloisoquinoline and tetrahydrobenzisoquinoline derivatives have been synthesized. Metal hydride reduction of the cyclic amino ketones, prepared by mild Friedel-Crafts type intramolecular acylation of N-naphthalenylmethyl amino acids, yielded pairs of diastereoisomeric alcohols. The absolute stereochemistry and some features of the n.m.r. spectra of hexahydrobenzopyrroloisoquinolines, tetrahydrobenzisoquinoline and those of their intermediates are discussed. 
