
TY  - JOUR
A1  - Gellert, E 
A1  - Kumar, N 
T1  - Stereospecific synthesis of hexahydrobenzopyrroloisoquinoline and tetrahydrobenzisoquinoline derivatives
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1984
VL  - 37
IS  - 4
SP  - 819
EP  - 829
KW  - 
UR  - https://doi.org/10.1071/CH9840819 
N2  - New optically active hexahydrobenzopyrroloisoquinoline and tetrahydrobenzisoquinoline derivatives have been synthesized. Metal hydride reduction of the cyclic amino ketones, prepared by mild Friedel-Crafts type intramolecular acylation of N-naphthalenylmethyl amino acids, yielded pairs of diastereoisomeric alcohols. The absolute stereochemistry and some features of the n.m.r. spectra of hexahydrobenzopyrroloisoquinolines, tetrahydrobenzisoquinoline and those of their intermediates are discussed. 
ER  -

