
%0 Journal Article
%A Bremer, J 
%A Moore, WJ 
%T N.M.R. studies of myelin basic protein. XII. Spectra in aqueous solution of a synthetic octapeptide encephalitogenic in the Lewis rat
%J Australian Journal of Chemistry
%D 1984/07/01
%V 37
%N 7
%P 1427-1435
%K 
%R https://doi.org/10.1071/CH9841427
%U https://www.publish.csiro.au/paper/CH9841427 
%X A synthetic peptide Ala-Gln-Arg-Pro-Gln-Asp-Glu-Asn encephalitogenic in the Lewis rat has been studied in aqueous solutions by 1H and 13C n.m.r. The configuration about the Arg-Pro peptide bond is > 99% trans. The temperature dependences and titration shifts of NH resonances areconsistent with occurrence of a number of intramolecular hydrogen bonds, leading to an unusually compact structure for a linear peptide in aqueous solution. 
