
%0 Journal Article
%A Crank, G 
%A Khan, HR 
%T Formation of Thioamide Derivatives from Reactions of Isothiocyanates with Oxazol-2-amines
%J Australian Journal of Chemistry
%D 1985/03/01
%V 38
%N 3
%P 447-458
%K 
%R https://doi.org/10.1071/CH9850447
%U https://www.publish.csiro.au/paper/CH9850447 
%X 4-Substituted oxazol-2-amines react with isothiocyanates to give products having a thioamide function at C5. The reaction is considered to be an electrophilic process in competition with the usual reaction of the amino group with the isothiocyanate . The nature of the isothiocyanate and the type of substituent at C4 affect the amount of the thioamide product formed. Some chemical properties of the thioamides are also investigated. 
