
%0 Journal Article
%A Waring, P 
%A Armarego, WLF 
%T Pterins. X. A New Preparation of 6-Hydroxymethylpterin from 6-Methylpterin
%J Australian Journal of Chemistry
%D 1985/04/01
%V 38
%N 4
%P 629-631
%K 
%R https://doi.org/10.1071/CH9850629
%U https://www.publish.csiro.au/paper/CH9850629 
%X 6-Hydroxymethylpterin was prepared in c. 80% overall yield via 2- acetamido-6-methylpteridin-4(3H)-one, oxidation with lead tetraacetate to 2-acetamido-6-acetoxymethylpteridin-4(3H)-one and hydrolysis. The 2-acetamido-6-methylpterin was prepared isomerically pure by acetylation of a mixture of 6- and 7-methylpterin prepared by condensation of 2,5,6-triaminopyrimidin-4(3H)-one with methylglyoxal at 0-5&#176;. Under these conditions the ratio of 6-methyl- to 7-methylpterin is considerably improved (9 : 1). 
