
%0 Journal Article
%A Grimmett, MR 
%A Vanhorik, ET 
%A Kulkarni, SR 
%T Alkylation of 4-Nitroimidazole-5-Thiol With Alpha,Omega-Dihalides to Form Bicyclic Derivatives
%J Australian Journal of Chemistry
%D 1985/12/01
%V 38
%N 12
%P 1873-1877
%K 
%R https://doi.org/10.1071/CH9851873
%U https://www.publish.csiro.au/paper/CH9851873 
%X The ammonium salt of 4-nitroimidazole-5-thiol is alkylated at N and S by 1,2-dichloroethane, 1,3-dibromopropane, and 1,4-dibromobutane to give bicyclic products. These cyclic thioethers can be oxidized to the sulfones , and brominated in the imidazole ring, while the bromine atom is subject to nucleophilic displacement by piperidine. 
