
TY  - JOUR
A1  - Grimmett, MR 
A1  - Vanhorik, ET 
A1  - Kulkarni, SR 
T1  - Alkylation of 4-Nitroimidazole-5-Thiol With Alpha,Omega-Dihalides to Form Bicyclic Derivatives
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1985
VL  - 38
IS  - 12
SP  - 1873
EP  - 1877
KW  - 
UR  - https://doi.org/10.1071/CH9851873 
N2  - The ammonium salt of 4-nitroimidazole-5-thiol is alkylated at N and S by 1,2-dichloroethane, 1,3-dibromopropane, and 1,4-dibromobutane to give bicyclic products. These cyclic thioethers can be oxidized to the sulfones , and brominated in the imidazole ring, while the bromine atom is subject to nucleophilic displacement by piperidine. 
ER  -

