
%0 Journal Article
%A Martin, RF 
%A Pardee, M 
%A Kelly, DP 
%A Mack, POL 
%T Synthesis and Characterization of 2-Iodo-4-[5&#8242;-(4'&#8243;-Methylpiperazin-1'&#8243;-yl)-2&#8242;,5&#8242;-bi-1h-Benzimidazol-2 &#8242;-Yl]Phenol (iodoHoechst 33258) and 2,5-Disubstituted Benzimidazole Model Compounds
%J Australian Journal of Chemistry
%D 1986/02/01
%V 39
%N 2
%P 373-381
%K 
%R https://doi.org/10.1071/CH9860373
%U https://www.publish.csiro.au/paper/CH9860373 
%X The product of iodination of the DNA-binding dye Hoechst 33258,4-[5&#8242;- (4&#8242;&#8242;&#8242;-methylpiperazin-1&#8242;&#8242;&#8242;-yl)-2&#8242;,5&#8242;-bi-1H-benzimidazol-2&#8242;-yl]phenol (1), has been identified as the monoiodo derivative, i.e. 2-iodo-4-[5&#8242;- (4&#8242;&#8242;&#8242;-methylpiperazin-1&#8242;&#8242;&#8242;-yl)-2&#8242;,5&#8242;-bi-1H-benzimidazol-2&#8242;-yl]phenol (2), by mass spectrometry and by comparison of the 1H and 13C n.m.r . spectra of (1) and (2) with those of 2,5-disubstituted benzimidazole model compounds (3) and (4). 
