
TY  - JOUR
A1  - Martin, RF 
A1  - Pardee, M 
A1  - Kelly, DP 
A1  - Mack, POL 
T1  - Synthesis and Characterization of 2-Iodo-4-[5&#8242;-(4'&#8243;-Methylpiperazin-1'&#8243;-yl)-2&#8242;,5&#8242;-bi-1h-Benzimidazol-2 &#8242;-Yl]Phenol (iodoHoechst 33258) and 2,5-Disubstituted Benzimidazole Model Compounds
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1986
VL  - 39
IS  - 2
SP  - 373
EP  - 381
KW  - 
UR  - https://doi.org/10.1071/CH9860373 
N2  - The product of iodination of the DNA-binding dye Hoechst 33258,4-[5&#8242;- (4&#8242;&#8242;&#8242;-methylpiperazin-1&#8242;&#8242;&#8242;-yl)-2&#8242;,5&#8242;-bi-1H-benzimidazol-2&#8242;-yl]phenol (1), has been identified as the monoiodo derivative, i.e. 2-iodo-4-[5&#8242;- (4&#8242;&#8242;&#8242;-methylpiperazin-1&#8242;&#8242;&#8242;-yl)-2&#8242;,5&#8242;-bi-1H-benzimidazol-2&#8242;-yl]phenol (2), by mass spectrometry and by comparison of the 1H and 13C n.m.r . spectra of (1) and (2) with those of 2,5-disubstituted benzimidazole model compounds (3) and (4). 
ER  -

