
TY  - JOUR
A1  - Burgess, VA 
A1  - Easton, CJ 
T1  - Reaction of N-Benzoyl-2-bromoglycine Methyl Ester With Deprotonated Nitroalkanes: Synthesis of &#946;-Nitro and &#945;,&#946;-Dehydro Amino Acid Derivatives
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1988
VL  - 41
IS  - 7
SP  - 1063
EP  - 1070
KW  - 
UR  - https://doi.org/10.1071/CH9881063 
N2  - N-Benzoyl-2-bromoglycine methyl ester (1) reacted with the alkyl nitronates (2a-e) to give the corresponding &#946;-nitro amino acid derivatives (4a-e). Elimination reactions of (4a-d) afforded the &#945;,&#946;-dehydro amino acid derivatives (5a-d). Treatment of the &#946;- nitrovaline derivative (4b) with tributyltin hydride gave the valine derivative (8). Reduction of the &#946;- nitroalanine derivative (4a) gave the &#946;- aminoalanine derivative (9), characterized by hydrolysis to 2,3- diaminopropionic acid hydrochloride. 
ER  -

