
TY  - JOUR
A1  - Deady, LW 
A1  - Ganakas, AM 
A1  - Ong, BH 
T1  - Ethoxycarbonylation of &#945;-Cyano-o-toluonitrile and Cyclization to Isoquinolines and Pyrimido[4,5-c]isoquinolines
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1989
VL  - 42
IS  - 7
SP  - 1029
EP  - 1034
KW  - 
UR  - https://doi.org/10.1071/CH9891029 
N2  - &#945; -Cyano-o-toluonitrile is a-ethoxycarbonylated with ethyl chloroformate and 4-dimethylamino- pyridine, and cyclized to ethyl 3-amino-1-bromoisoquinoline-4-carboxylate. This is further functionalized, and examples of third-ring annulation to pyrimido [4,5-c] isoquinolines are reported. 
ER  -

