
%0 Journal Article
%A Barlin, GB 
%A Jiravinyu, C 
%T Potential Antimalarials. IX. Di-mannich Bases of 4-(7&#8242;-trifluoro-methylquinazolin-4&#8242;-ylamino)phenol and 4-(7&#8242;-Trifluoromethylquinolin-4&#8242;-ylamino)phenol
%J Australian Journal of Chemistry
%D 1990/02/01
%V 43
%N 2
%P 311-319
%K 
%R https://doi.org/10.1071/CH9900311
%U https://www.publish.csiro.au/paper/CH9900311 
%X Syntheses are reported for a series of di-Mannich bases of 4-(7&#8242;-trifluoromethylquinazolin-4&#8242;-ylamino)phenol derived from 4-chloro-7-trifluoromethylquinazoline with the di-Mannich bases of 4-aminophenol. Some analogous quinolines were prepared similarly. When tested for antimalarial activity against Plasmodium falciparum in vitro, the quinazolines were rather less active than the corresponding quinolines. 
