
TY  - JOUR
A1  - Barlin, GB 
A1  - Jiravinyu, C 
T1  - Potential Antimalarials. IX. Di-mannich Bases of 4-(7&#8242;-trifluoro-methylquinazolin-4&#8242;-ylamino)phenol and 4-(7&#8242;-Trifluoromethylquinolin-4&#8242;-ylamino)phenol
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1990
VL  - 43
IS  - 2
SP  - 311
EP  - 319
KW  - 
UR  - https://doi.org/10.1071/CH9900311 
N2  - Syntheses are reported for a series of di-Mannich bases of 4-(7&#8242;-trifluoromethylquinazolin-4&#8242;-ylamino)phenol derived from 4-chloro-7-trifluoromethylquinazoline with the di-Mannich bases of 4-aminophenol. Some analogous quinolines were prepared similarly. When tested for antimalarial activity against Plasmodium falciparum in vitro, the quinazolines were rather less active than the corresponding quinolines. 
ER  -

