
%0 Journal Article
%A Prager, RH 
%A Tsopelas, C 
%T Approaches to the Synthesis of 5-Benzylidene-2-imidazolin-4-ones
%J Australian Journal of Chemistry
%D 1990/02/01
%V 43
%N 2
%P 367-374
%K 
%R https://doi.org/10.1071/CH9900367
%U https://www.publish.csiro.au/paper/CH9900367 
%X Aromatic aldehydes , but not ketones, can be condensed with glycocyamidine . The corresponding alkylbenzylideneglycocyamidines may be made from glycidic esters by reaction with guanidine, followed by cyclization with acetic anhydride. A number of mono- and di -acetylated derivatives of 6,7-dihydropyrrolo[2,3-c]azepine-4,8(1H,5H)- dione have been prepared, but failed to undergo the Darzens reaction. Bromo- and iodo-2-arylazoimidazoles, protected on nitrogen by the methoxyethoxymethyl group, failed to undergo clean lithiation. 
