
%0 Journal Article
%A Barlin, GB 
%A Jiravinyu, C 
%T Potential Antimalarials. XI. 4'-Chloro-3-(substituted amino)-methyl-5-(7-trifluoromethylquinolin-4-ylamino)biphenyl-2-ols
%J Australian Journal of Chemistry
%D 1990/07/01
%V 43
%N 7
%P 1301-1307
%K 
%R https://doi.org/10.1071/CH9901301
%U https://www.publish.csiro.au/paper/CH9901301 
%X Syntheses are reported for 3-(t-butylamino)methyl-4&#8242;-chloro-5-(7&#8242;-trifluoromethylquinolin-4&#8242;-(ylamino)biphenyl-2-ol (5b) and analogous Mannich bases from diethylamine, pyrrolidine, piperidine, 3- and 4-methylpiperidine, 4-benzylpiperidine and 4-benzylpiperazine via N- substituted 3-aminomethyl-4&#8242;-chloro-5-nitrobiphenyl-2-ols (9). These compounds have been prepared for evaluation as antimalarials. 
