
%0 Journal Article
%A Bali, DKL 
%A Liokas, V 
%A Garson, MJ 
%A Faulkner, DJ 
%T Structural and Stereochemical Studies on Brominated Meroterpenoids From the Dictyoceratid Sponge <I>Cacospongia</I> sp.
%J Australian Journal of Chemistry
%D 1990/12/01
%V 43
%N 12
%P 2009-2020
%K 
%R https://doi.org/10.1071/CH9902009
%U https://www.publish.csiro.au/paper/CH9902009 
%X The structures of seven minor metabolites, (5)-(11), from the encrusting sponge Cacospongia sp. Were deduced by 1H, 13C and mass spectrometric data. Compounds (5)-(7) are hydroxy derivatives of the previously isolated tribromocacoxanthene (1); their relative stereochemistry was determined from 1H-1H coupling information. Compounds (8)-(11) represent an alternative cyclization mode of a cyclocymopol-related precursor (15) and possess a spiro-fused bicyclic ring system; the relative stereochemistry of (8)-(10) was deduced by 1H n.O.e. difference spectroscopy. The biological role of brominated meroterpenoids in Cacospongia sp. is discussed. 
