
TY  - JOUR
A1  - Grant, PK 
A1  - Hanton, LR 
A1  - Tsai, SF 
A1  - Yap, TM 
T1  - Intramolecular Participation Reactions in Labda-8(17),14-dien-13-ol (Manool) Derivatives
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1991
VL  - 44
IS  - 3
SP  - 433
EP  - 446
KW  - 
UR  - https://doi.org/10.1071/CH9910433 
N2  - Lewis acid treatment of a series of hydroxy  epoxides promoted intramolecular  nucleophilic epoxide opening to give hydroxy cyclic ethers. The regioselectivity of epoxide opening is controlled by a preference for SN2 attack at the more accessible epoxide carbon, provided this does not involve the formation of a strained ether ring. An intramolecular acetate transfer occurs in order to achieve the regioselective opening. 
ER  -

