
%0 Journal Article
%A Janowski, WK 
%A Prager, RH 
%T Potential GABA<sub>B</sub> Receptor Antagonists. IV. Synthesis of 1-[2-Amino-1-(4-chlorophenyl)ethyl]-3-oxo-1,3-dihydro-isobenzofuran-1-yl phosphonic Acid
%J Australian Journal of Chemistry
%D 1991/03/01
%V 44
%N 3
%P 477-480
%K 
%R https://doi.org/10.1071/CH9910477
%U https://www.publish.csiro.au/paper/CH9910477 
%X The diastereoselective addition of dimethyl 3-oxo-1,3-hydroisobenzofuran-1-ylphosphonate to nitrostyrene and p- chloronitrostyrene is reported, as is the subsequent conversion of the Michael adducts into 1-[2-amino-1-phenylethyl]-3-oxo-1,3-dihydroisobenzofuran-1-ylphosphonic acid, and 1-[2-amino-1-(4-chlorophenyl)ethyl]-3-oxo-1,3 dihydroisobenzofuran-1-ylphosphonic acid respectively. 
