
TY  - JOUR
A1  - Bray, AM 
A1  - Kelly, DP 
A1  - Lim, TK 
T1  - Dna-Binding Compounds. IV. Synthesis and Solution Conformation of a Novel Macrocyle Formed by Coupling of the Side-Chains of Adjacent L-Lysine Residues
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1991
VL  - 44
IS  - 11
SP  - 1649
EP  - 1658
KW  - 
UR  - https://doi.org/10.1071/CH9911649 
N2  - The novel macrocyclic  dilysine derivatives (8S,11S)-11-t-butoxycarbonylamino-2,10-dioxo-1,3,9-triazacyclopentadecane-8-carboxylic acid methyl (5) and t-butyl (6) esters were prepared by coupling of the &#1108;-amino groups of adjacent lysine residues of the esters of Boc-Lys-Lys-OR with 1,1&#8242;-carbonyldiimidazole under mild conditions. The conformation of (6) in dimethyl sulfoxide solution was determined by the use of a variety of one- and two-dimensional n.m.r. techniques. 
ER  -

