
TY  - JOUR
A1  - Camp, D 
A1  - Jenkins, ID 
T1  - The Mechanism of the Mitsunobu Reaction. III. The Use of Tributylphosphine
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1992
VL  - 45
IS  - 1
SP  - 47
EP  - 55
KW  - 
UR  - https://doi.org/10.1071/CH9920047 
N2  - 31P n.m.r . studies indicate that, when tributylphosphine is used in the Mitsunobu  esterification reaction, clean formation of a single intermediate, an alkoxyphosphonium carboxylate, is apparent. In the absence of acid, at least two species are observed, a dialkoxytributylphoshorane and the corresponding alkoxyphosphonium salt. The order of mixing of the reagents can dramatically change the mechanism and stereochemistry of esterification reactions. 
ER  -

