
%0 Journal Article
%A Easton, CJ 
%A Tan, EW 
%A Ward, CM 
%T Synthesis of Cyclopropyl Amino Acid Derivatives
%J Australian Journal of Chemistry
%D 1992/02/01
%V 45
%N 2
%P 395-402
%K 
%R https://doi.org/10.1071/CH9920395
%U https://www.publish.csiro.au/paper/CH9920395 
%X Derivatives of &#945;,&#946;-methanovaline, &#945;,&#946;-methanophenylalanine and &#946;-methyl-&#945;&#946;methanoalanine have been prepared by regioselective side-chain functionalization of suitably protected amino acid derivatives, followed by cyclization with either sodium hydride or 1,8-diazabicyclo[5.4.O]undec-7-ene. The approach used in this work illustrates a method for the synthesis of cyclopropyl amino acid derivatives which is complementary to existing procedures. 
