
%0 Journal Article
%A Bhindi, AK 
%A Chiswell, B 
%A Rauchle, GP 
%T Site of Chlorine Interaction With a Cation-Exchange Resin (Chelex-100)
%J Australian Journal of Chemistry
%D 1992/07/01
%V 45
%N 7
%P 1143-1153
%K 
%R https://doi.org/10.1071/CH9921143
%U https://www.publish.csiro.au/paper/CH9921143 
%X X-Ray photoelectron spectroscopy, 13C and 1H solution-state n.m.r., and 13C solid-state n.m.r. were used in chlorination studies on compounds, which act as models for the exchange group and the styrene divinylbenzene copolymer backbone of Chelex-100, to determine the site and mechanism of chlorine attack. Results indicate that the resin cleaves upon chlorination, and a cleavage mechanism, involving initial attack by chlorine on the exchange group imine nitrogen electron lone pairs, is proposed. The N-halo quaternary species formed loses a molecule of hydrogen chloride to give a Schiff base, which undergoes hydrolysis to an aldehyde and an ammonium salt. 
