
%0 Journal Article
%A Perich, JW 
%A Johns, RB 
%T Solution Phase Synthesis and Conformational Analysis of Glu-Ser-Leu-Ser-Ser-Ser-Glu-Glu-NHMe and Its Peptide Congeners (Non-Phosphorylated Region 14-21 of Bovine &#946;-Casein A<sub>2</sub>)
%J Australian Journal of Chemistry
%D 1992/11/01
%V 45
%N 11
%P 1857-1869
%K 
%R https://doi.org/10.1071/CH9921857
%U https://www.publish.csiro.au/paper/CH9921857 
%X The octapeptide H-Glu-Ser-Leu-Ser-Ser-Ser-Glu-Glu-NHMe.CF3CO2H and its five shorter peptide congeners (from tripeptide to heptapeptide ) were prepared in high yield and purity by the Boc mode of solution phase peptide synthesis followed by palladium- catalysed hydrogenolytic deprotection of the six protected peptides in 50% CF3CO2H/CH3CO2H solution. The analysis of the six peptides by 13C n.m.r. spectroscopy and C18 reversed-phase chromatography suggested that a structural arrangement commenced at the hexapeptide stage and was considered to be due to the formation of a &#946;-turn conformation. 
