
TY  - JOUR
A1  - Barlin, GB 
A1  - Nguyen, TMT 
A1  - Kotecka, B 
A1  - Rieckmann, KH 
T1  - Potential Antimalarials. XVII. Di- and Mono-Mannich Bases of 2(and 4)-[2(and 8)-Trifluoromethylquinolin-4-ylamino]phenol
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1993
VL  - 46
IS  - 1
SP  - 21
EP  - 29
KW  - 
UR  - https://doi.org/10.1071/CH9930021 
N2  - Di- and mono-Mannich base derivatives of 2(and 4)-[2(and 8)-trifluoromethylquinolin-4-ylamino]phenols have been prepared for comparison with the 7-trifluoromethyl isomers in tests for antimalarial activity. The order of activity in in vitro tests against the FC-27 ( chloroquine -sensitive) strain of Plasmodium falciparum was 7-CF3 >> 8-CF3 > 2-CF3. 
ER  -

