
%0 Journal Article
%A Bell, KH 
%A Mccaffery, LF 
%T Regioselective Monomethylation of Unsymmetrical Naphthalenediols With Methanolic HCl
%J Australian Journal of Chemistry
%D 1993/05/01
%V 46
%N 5
%P 731-737
%K 
%R https://doi.org/10.1071/CH9930731
%U https://www.publish.csiro.au/paper/CH9930731 
%X Treatment of naphthalene-1,3-diol and naphthalene-1,7-diol with methanol containing dry hydrogen chloride at room temperature gives exclusively 3-methoxy-1-naphthol and 7-methoxy- 1-naphthol, respectively. Of the other two unsymmetrical naphthalenediols, the 1,2-isomer was unreactive and the 1,6-isomer gave a mixture of regioisomers under the same conditions. Two symmetrical diols (the 1,5- and 2,7-isomers) examined by the same procedure gave the monomethyl ethers in 60-70% yields. 
