
TY  - JOUR
A1  - Mcfadden, HG 
A1  - Huppatz, JL 
A1  - Halladay, PK 
T1  - Synthesis of Pyrazoles and Pyrazolo[1,5-a]pyrimidines From 3-Arylsulfonylaminoacrylates
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1993
VL  - 46
IS  - 6
SP  - 873
EP  - 886
KW  - 
UR  - https://doi.org/10.1071/CH9930873 
N2  - 3-Arylsulfonylaminopyrazole-4-carboxamides and -carboxylates were synthesized from 3-arylsulfonylamino-3-methylthiocyanoacrylate derivatives as potential herbicidal inhibitors of the enzyme acetohydroxyacetic acid synthase (AHAS). Some of these compounds were reacted further with acetylacetone, giving 3-arylsulfonylaminopyrazolo[1,5-a]pyrimidine-3-carboxamides by a novel route. During the synthesis of the 3-arylsulfonylaminopyrazole-4-carboxylates, the arylsulfonylamino group was observed to function as a leaving group. This phenomenon is of potential synthetic utility and was found to be sensitive to solvent and steric factors and was also observed with a methylsulfonylamino group. None of the compounds tested was biologically active. 
ER  -

