
TY  - JOUR
A1  - Brown, SE 
A1  - Coates, JH 
A1  - Coghlan, DR 
A1  - Easton, CJ 
A1  - Vaneyk, SJ 
A1  - Janowski, W 
A1  - Lepore, A 
A1  - Lincoln, SF 
A1  - Luo, Y 
A1  - May, BL 
A1  - Schiesser, DS 
A1  - Wang, P 
A1  - Williams, ML 
T1  - Synthesis and Properties of 6<sup>A</sup>-Amino-6<sup>A</sup>-deoxy-&#945; and &#946;-cyclodextrin
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1993
VL  - 46
IS  - 6
SP  - 953
EP  - 958
KW  - 
UR  - https://doi.org/10.1071/CH9930953 
N2  - The monotosylates obtained by treatment of &#945;- and &#946;- cyclodextrin with p- methylbenzenesulfonyl chloride reacted with ammonia to give the title compounds. These amines are of unusually low basicity , with pKa values of 8.70 and 8.72, respectively. In water at 25&#176;, the hydrochloride salt of the amine derived from &#946;- cyclodextrin is approximately 40 times more soluble than &#946;-cyclodextrin and, through complexation, the salt increases the solubility of Nabumetone over 800 times. 
ER  -

