
%0 Journal Article
%A Amiet, RG 
%A Kalafatis, N 
%A Macrides, T 
%T On the Synthesis of Scymnol
%J Australian Journal of Chemistry
%D 1993/09/01
%V 46
%N 9
%P 1347-1354
%K 
%R https://doi.org/10.1071/CH9931347
%U https://www.publish.csiro.au/paper/CH9931347 
%X Reinvestigation of a reported synthesis of scymnol (5&#946;-cholestane-3&#945;,7&#945;,12&#945;,24,26,27-hexol) has cast doubt on the success of that synthetic route. A modified synthetic pathway has been developed and scymnol, racemic at C24, has been unequivocally prepared from cholic acid. Extensive proton and 13C n.m.r. spectroscopy has been used to confirm the structure of the product. A new, simple method of desulfation of natural scymnol sufate has been developed. 
