
%0 Journal Article
%A Chen, QP 
%A Deady, LW 
%A Mackay, MF 
%T A Comparison of Chemical Reactivity in Some Benzo[b]Naphthyridines (Azaacridines)
%J Australian Journal of Chemistry
%D 1993/12/01
%V 46
%N 12
%P 1909-1918
%K 
%R https://doi.org/10.1071/CH9931909
%U https://www.publish.csiro.au/paper/CH9931909 
%X Some comparisons between four series of benzo [b][1,x] naphthyridines (x=5-8) have been made. Bromination in acetic acid gave almost exclusive reaction &#946; to the nitrogen in the outer pyrido ring. Basic silver oxide oxidation of the centre ring occurred in the order x = 6 > 8 > 7 > 5. Methylation occurred on the pyrido nitrogen, the relative nucleophilicities paralleling those of the corresponding naphthyridines . One methiodide (x = 6) underwent an interesting dimerization in solution and the structure of the product was determined by X-ray crystallography. 
