
%0 Journal Article
%A Almassi, F 
%A Ghisalberti, EL 
%A Skelton, BW 
%A White, AH 
%T Structural Study of Dehydrocurvularin, an Inhibitor of Microtubule Assembly
%J Australian Journal of Chemistry
%D 1994/06/01
%V 47
%N 6
%P 1193-1197
%K 
%R https://doi.org/10.1071/CH9941193
%U https://www.publish.csiro.au/paper/CH9941193 
%X The solid-state structure of the fungal metabolite E-dehydrocurvularin (2), an inhibitor of microtubule assembly, has been determined by a single-crystal room-temperature X-ray study for comparison with curvularin (1). Crystals of (2) are orthorhombic, P212121, a 17.757(9), b 10.031(6), c 8.069(4) &#506;, Z = 4; R was 0.060 for 988 independent 'observed' [I > 3&#963;(I)] diffractometer reflections. The results of this study show that (1) and (2) adopt opposite helicity in the solid state. 
