
%0 Journal Article
%A Brown, SE 
%A Easton, CJ 
%A Lincoln, SF 
%T Complexation of Fluorinated Amino Acid Derivatives by &#946;- and &#947;-Cyclodextrin in Aqueous Solution. A <sup>19</sup>F Nuclear Magnetic Resonance Study
%J Australian Journal of Chemistry
%D 1995/03/01
%V 48
%N 3
%P 505-513
%K 
%R https://doi.org/10.1071/CH9950505
%U https://www.publish.csiro.au/paper/CH9950505 
%X A 19F n.m.r. study shows that the &#946;-cyclodextrin complexes of deprotonated &#945;-(p- fluorophenyl ) glycine, N-acetyl-&#945;-(p- fluorophenyl ) glycine , deprotonated N-acetyl-&#945;-(p- fluorophenyl ) glycine , and N-(p- fluorobenzoyl ) valine  are characterized by stability constants KR/dm3 mol-1 and Ks/dm3 mol-1 =13±2 and 21±3, 34±1 and 35±2, 12±1 and 12± 1, and 84±2 and 93±2, respectively, where the first and second of each pair of values refers to the complex formed by the R and S enantiomers of the fluorinated amino acid derivatives, respectively, in 10% aqueous D2O solution at 295.5 K and I = 0.10 mol dm-3. A comparison of these data and the associated 19F chemical shift data with those for the analogous &#945;- and &#947;- cyclodextrin complexes provides an insight into the factors affecting the stabilities and structures of these complexes. 
