
TY  - JOUR
A1  - Brown, SE 
A1  - Easton, CJ 
A1  - Lincoln, SF 
T1  - Complexation of Fluorinated Amino Acid Derivatives by &#946;- and &#947;-Cyclodextrin in Aqueous Solution. A <sup>19</sup>F Nuclear Magnetic Resonance Study
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1995
VL  - 48
IS  - 3
SP  - 505
EP  - 513
KW  - 
UR  - https://doi.org/10.1071/CH9950505 
N2  - A 19F n.m.r. study shows that the &#946;-cyclodextrin complexes of deprotonated &#945;-(p- fluorophenyl ) glycine, N-acetyl-&#945;-(p- fluorophenyl ) glycine , deprotonated N-acetyl-&#945;-(p- fluorophenyl ) glycine , and N-(p- fluorobenzoyl ) valine  are characterized by stability constants KR/dm3 mol-1 and Ks/dm3 mol-1 =13±2 and 21±3, 34±1 and 35±2, 12±1 and 12± 1, and 84±2 and 93±2, respectively, where the first and second of each pair of values refers to the complex formed by the R and S enantiomers of the fluorinated amino acid derivatives, respectively, in 10% aqueous D2O solution at 295.5 K and I = 0.10 mol dm-3. A comparison of these data and the associated 19F chemical shift data with those for the analogous &#945;- and &#947;- cyclodextrin complexes provides an insight into the factors affecting the stabilities and structures of these complexes. 
ER  -

