
TY  - JOUR
A1  - Gray, JE 
A1  - Maclean, SA 
A1  - Reinsborough, VC 
T1  - Limitations of the Phenolphthalein Competition Method for Estimating Cyclodextrin Binding Constants
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1995
VL  - 48
IS  - 3
SP  - 551
EP  - 556
KW  - 
UR  - https://doi.org/10.1071/CH9950551 
N2  - The phenolphthalein competitive spectrophotometric technique was used to obtain binding constants for cyclodextrin complexes for a variety of both inclusates and cyclodextrins . The former included alkane-1-sulfonates (C5-C12), alkyl sulfates (C6, C8, C12) and several heterocyclic ligands, and the latter included &#946;-cyclodextrin, dimethyl-&#946;-cyclodextrin and &#947;- cyclodextrin . The technique was not successful for either &#945;- cyclodextrin or trimethyl -&#946;- cyclodextrin inclusion complexes, or with many primary amines and quaternary ammonium cationic surfactants. However, for many colourless inclusates this method is a simple, convenient, reliable route to cyclodextrin binding constants. 
ER  -

